One Line Laboratory Services

Human Exposure Analysis (Biomonitoring)

Human Exposure Analysis (Biomonitoring)

The need to assess the real health effects from exposure to chemicals is hampered by our inadequate understanding of what chemicals people are exposed to and to what degree these exposures might cause short term (acute) or long term (chronic) adverse health effects.

tourniqutte

What is Human Biomonitoring?

Human Biomonitoring is the measurement of toxic substances in the human body. The purpose of Human Biomonitoring is to determine if you have been exposed to a toxic substance, how much of that toxic substance is in your body, and whether the amount of that toxic substance in your body is enough to cause an adverse health effect. Toxic substances generally enter the body through one of three routes: ingestion, inhalation, or dermal penetration.

The amount of substance available for toxic action depends on a number of factors. In most cases, the substance is absorbed to some degree into the bloodstream where it is distributed throughout the body. At this point, toxic substances have three possible fates: they are stored, excreted, or metabolized. Most chemicals undergo some combination of all three. Storage typically occurs in a reservoir such as bone or adipose tissue. Excretion involves the elimination of substances or their metabolites through urine, feces, saliva, sweat, or exhalation. Substances that are metabolized are often chemically altered to make excretion of the substance easier.

exposure-assesment

The time (antecedent or present), duration, and intensity of exposure to a particular substance will dictate the choice of human tissue that is sampled to monitor the substance or its metabolites. Most Human Biomonitoring involves sampling humans for whole blood or serum and urine. However, meaningful results have been achieved from sampling saliva, feces, hair, nails, teeth, breath, and sweat. For example, when exposed to lead from paint, approximately 90 percent of lead absorbed will be stored in the bone over time and 10 percent is excreted, mostly through the urine, nails, and hair.

What Can AASlab Do for You?

AAS Laboratory is uniquely positioned to help you with a full range of professional services from design, development, and writing funding/grant proposals to preparing final consultative reports on sound scientific laboratory data.

Parameters Analysis

Saat ini AAS Laboratory sudah terakreditasi ISO 17025 oleh KAN, dengan demikian KETELUSURAN data pengukuran yang dilakukan dapat terjamin dengan Baik. Sealin itu, di dukung peralatan tercanggih di kelasnya seperti GCMS, HPLC dan Hybride Atomic Absorption Spectrophotometer dan TEnaga Ahli yang memang mempunyai Kompetensi di Bidangnya.

who